Journal of Clinical Cases

A Case Report Of Recurrent Multiple Myeloma Complicated With HIT On Dialysis

Yuan Chen, Shan Gao, Minqiu Lu, Bin Chu, Lei Shi, Qiuqing Xiang, Lijuan Fang, Yuehua Ding, Mengzhen Wang, Xi Liu, Xin Zhao, Kai Sun and Li Bao

Department
Hematology Department, Beijing Jishuitan Hospital, Capital Medical University, No. 31 East Xinjiekou Street, Xicheng District, Beijing,100035, China

Corresponding Author: Ruiqing Xu

Abstract

1.1. Backgrount: At present, the application of heparin is becoming more and more widespread, the problems arising from the use of heparin are gradually exposed, and people are paying more and more attention to how to use heparin safely. Heparin-induced thrombocytopenia is a disease of thrombocytopenia caused by the use of heparin in the treatment process. Although this type of disease is relatively rare in clinical, it can cause dangerous situations.
1.2. Case presentation: A 75-year-old man was admitted to the hospital due to a recurrence of multiple myeloma. He had to undergo hemodialysis due to high creatinine. During the dialysis, platelets drop to extremely low levels and iliac vein thrombosis appeared. It was found that the patient used heparin to seal the tube during dialysis, which resulted in the heparininduced thrombocytopenia. After stopping heparin and using alternative anticoagulation, the patient’s platelet count recovered gradually.
1.3. Conclusions: HIT is a relatively hidden but very dangerous disease, which requires rapid and correct judgment and measures. When the patient has HIT and the platelet is extremely reduced, after weighing the risk of thrombosis, alternative anticoagulation can be performed. The drug, Argatroban, can still exert an anticoagulation effect even when used in low doses.