Journal of Clinical Cases

Aplastic Anemia In Two Siblings Due To Use Of Organochlorine Pesticide Lindane

Kilinc Y, TuncelDS, AlmaciogluM and Ozkaya PK

Departments:
SANKO University, Faculty of Medicine, Department Of Pediatrics, Division of Pediatric Hematology, Adana City Hospital, SANKO University Faculty of Medicine, Department of Pediatrics.
City Hospital, Adana.
SANKO University, Dept. Of Pediatrics.

Corresponding Author: Dr. Yurdanur Kilinc

ABSTRACT

Introduction: Aplastic anemia (AA) is a hematopoietic disorder with high risk of death and characterized by pancytopenia and hypocellularity of bone marrow. The suspected etiological factors are the losses and/or functional disorders of the stem cells, ultrastructural defects of bone marrow elements, abnormalities of regulatory growth factors in blood and autoimmune inhibition of hematopoiesis [1]. Although the incidence of aplastic anemia is [3-5] per million in the general population, [2-4] per million in childhood under 15 years and is more frequent in the eastern countries compared with western countries; the Asiatic populations sare [2-3] fold more than the other populations [3-7]. Also, illiterate people have higher risk for acquired aplastic anemia