Journal of Clinical Cases

Concomitant Presentation Of Adult Sjögren’s Syndrome With Lupus Anticoagulant-Hypoprothrombinemia Syndrome: A Case Report

BinHan Liu, Yi Liu

Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.

Corresponding Author: Yi Liu

ABSTRACT

In the context of LAHS, a rare hemorrhagic disorder linked with systemic lupus erythematosus (SLE) and viral infections, we report an adult patient diagnosed with primary Sjögren’s syndrome who later developed LAHS. The patient responded positively after undergoing steroid therapy and receiving the immunosuppressive agentcyclophosphamide. Remarkably, a 2-month follow-up revealed significant recovery. This case underscores the unique coexistence of Sjögren’s syndrome and LAHS and the efficacy of the combined treatment approach.

Keywords:Sjögren’s syndrome, LAHS, factor II deficiency, lupus anticoagulant, steroids, cyclophosphamide.