Journal of Clinical Cases

Increased Risk Of Ovarian Cysts With Compound Norethindrone Enanthate Immediately After Abortion

Jiao Fan and Yumei Wang

Department
Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University

Corresponding Author: Yumei Wang

ABSTRACT

1.1. Objective:To assess the effect of compound norethindrone enanthate injections immediately after abortion on ovarian cyst formation and post-abortion recovery in women who have had an abortion.
1.2. Methods:Data were collected from January 2023-June 2023 from patients who were injected with compound norethindrone enanthate immediately after abortion and patients who were not injected in our department, and clinical data and short-term post-abortion recovery of patients who were injected with compound norethindrone enanthate immediately after abortion and patients who were not injected were retrospectively analyzed.
1.3. Results:The number of days of post-abortion bleeding was mainly 1-3 days in patients who were injected with norethindrone enanthate immediately after abortion, while the number of days of post-abortion bleeding was mainly 4-7 days in patients who were not injected; the amount of postabortion bleeding in the injected group was significantly less than that in the non-injected group, and the injected group did not see any patients suffering from post-abortion bleeding in large quantities (total amount of >10 ml). The injection of compound norethindrone enanthate immediately after abortion did not affect HCG conversion after abortion. Moreover, the use of exogenous hormone (norethindrone enanthate) allowed patients in the injection group to return to menstruation at a median of 17 days after the abortion. Although patients in the injection group were more likely to develop ovarian cysts than those in the non-injected group, there were no significant differences in the number of days of post-abortion bleeding, the amount of bleeding, the rate of urinary HCG conversion, the time to return to the first menstrual period, the duration of menstruation, the amount of menstruation, or the thickness of the uterine endometrium between the patients who developed an ovarian cysts and those who did not develop ovarian cysts in patients who accepted injection of norethindrone enanthate.
1.4. Conclusion: The injection of compound norethindrone enanthate immediately after abortion can increase the occurrence of functional ovarian cysts in abortion patients, but it can significantly reduce the time and amount of vaginal bleeding after abortion, and due to the effect of hormone withdrawal, the time of the first menstrual period after abortion was significantly earlier than that of patients in the non-injected group.