Journal of Clinical Cases

The Importance Of Lactate Dehydrogenase Isomers In The Diagnosis Of Uterine Tumors

Kampioni M. Lach A, Chmaj-Wierzchowska K, Tomczyk K and Wilczak M*

Gynecology and Obstetrics Department, Minimally Invasive Operative Gynecology Subdepartment, Diagnostic and Monitoring Subdepartment IA and IB, Heliodor Święcicki Gynecology and Obstetrics Clinical Hospital in Poznań, Karol Marcinkowski Medical University in Poznań

Corresponding Author: Maciej Wilczak

INTRODUCTION

Uterine myomas are the most common benign uterine tumors in women of reproductive age [1]. These lesions rarely appear before puberty, and their incidence decreases with menopause. Factors that increase overall exposure to estrogen throughout life, such as obesity or early first menstruation, among others, increase the risk of uterine myomas in women. On the other hand reduced estrogen exposure found during exercise and increased number of childbirth, have a protectective effect [2]. Heavy menstrual bleeding often leading to patient anemia and a feeling of pressure or distension in the pelvis are the main symptoms associated with myomas [3]. Other symptoms include infertility, increased urinary frequency or incontinence, constipation, abdominal bloating, dyspareunia and fatigue (due to anemia from heavy bleeding) [4,5]. The spectrum and severity of symptoms often depends on the size, location and number of tumors in the uterus. [6] Currently, there are various options for the effective treatment of myomas, ranging from the most conservative approach to the most invasive: symptomatic treatment with oral contraceptive pills or levonorgestrel-releasing IUDs, treatment with ulipristal acetate, HIFU, embolization of the myoma, surgical removal of the lesion (hysteroscopy, laparoscopy, laparotomy) and removal of the affected uterus (laparoscopy, laporotomy). Various factors will influence a patient’s choice: personal preference, age, desire for pregnancy and future fertility, individual symptoms, and medical availability of various treatments. [7].