Journal of Clinical Cases

Transient Neurological Deficit and Severe Periorbital Reaction Following Routine Surgery: A Diagnostic Dilemma

Dr. Vaishali Vasant Deshpande¹, Dr. Akansha Sharma², Dr. Bhavna Rote ³, Dr. Lauren Berkow⁴

1. Consultant Anaesthesiologist, Jupiter Hospital, Pune, India
2. Associate Anaesthesiologist, Jupiter Hospital, Pune, India
3. Resident Anaesthesiologist, Jupiter Hospital, Pune, India
4. Consultant Anaesthesiologist, Harvard Medical Center, Boston, USA

Corresponding Author: Dr. Akansha Sharma,Associate Anaesthesiologist, Jupiter Hospital, Pune, India

ABSTRACT

We present the case of a 44-year-old woman who developed a sudden severe periorbital reaction and a neurological episode following revision ACL reconstruction surgery. Initially thought to be unrelated, the combination of angioedema and generalized seizure prompted an extensive differential diagnosis spanning anesthetic complications, metabolic causes, and even rare immune responses. Eventually, the most significant factor leading to all these events was identified as an unexpected allergy to adhesives. This case highlights the importance of gathering a comprehensive allergy history, including sensitivities to over-the-counter and cosmetic products, since even routine procedures can lead to unanticipated postoperative events.