Journal of Clinical Cases

Urothelial Carcinoma Of The Bladder Presenting With Abnormal Inguinal Metastasis

Hongyu Wang, Surong Hua

1. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Shuaifuyuan, Dongcheng District, Beijing 100730, China

Corresponding Author: Surong Hua and Hongyu Wang

ABSTRACT

Introduction:Inguinal lymph node metastasis in urothelial carcinoma is exceptionally rare. Here, we report three cases of bladder cancer with inguinal lymph node metastasis managed at our center since 1990. All patients underwent PET/CT scans, and in two cases, inguinal lymph node biopsies confirmed metastatic urothelial carcinoma. Metastasis from other primary sites, including external genitalia, was excluded. Notably, one elderly female presented with inguinal lymph node metastasis as the initial sign of recurrence. All three patients had a history of transurethral resection of bladder tumors (TURBT) and were diagnosed with high-grade urothelial carcinoma, subsequently receiving adjuvant chemotherapy. This report underscores the increased risk of distant metastasis and highlights the critical need for vigilant monitoring of patients with recurrent bladder cancer following repeated TURBT procedures.